용출시험기 용 Sinker를 소개합니다. - 3탄 - 본문
The choice of sinker will depend on the tablet or capsule. In general there are some guidelines that can be followed, however :
- The sinker should ideally not touch the tablet as this can effect the dissolution rate. They are available in different size to accommodate most capsule/tablet dimesions.
- A minimum amount of weight is preferable, just enough to have the desired effect
- Coated sinkers can be used where there may be a reaction between steel and the tablet
- Basket type sinkers can be used but care should be taken that the outer coating of the tablet does not clog the mesh.
- Wire spirals shoild be as wide as practically possible to avoid clogging which will effect the dissolution rate.
Japanese sinkers are specified by the JP & USP and have strict dimensions.
Dissolution Tester : Sinker
더 자세한 정보는 켐코코리아로 문의하세요~!
켐코코리아 주식회사
Tel. 043-215-2012
e-mail. ck@chemcokorea.com
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