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Suzuki-Miyaura Cross-Coupling Screnning Kits 본문

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Suzuki-Miyaura Cross-Coupling Screnning Kits

켐코코리아(주) 2022. 9. 13. 10:30

When a first attempt is unsuccessful, the endless combinations can make researching optimum reaction conditions overwhelming.

In order to facilitate the screening of common Suzuki-Miyaura reaction conditions, EvoluChem has released a series of high-throughput reaction screening kits combining common palladium sources, ligands and base combinations to achieve successful cross-coupling transformations.

 

 

Suzuki-Miyaura Cross-Coupling Screening Kits Protocol

The standard protocol is performed with 100 µl  substrates solution at 0.15M concentration, 10% catalyst and 2 base quivalents. Additional conditions can be investigated by changing the substrate concentration, or amount of base. You can choose between 2 different arrays of catalysts as well as between aqueous solutions of base or solid anhydrous bases.

1.  Prepare the substrate solution.

 

 

2.  Add to reaction vials containing the pre-weighed reagents and catalysts using a syringe.

3.  Place the reaction block on a standard stir/heat plate and set your reaction temperature.

 

 

4 Suzuki-Miyaura Screening Kits Available:

 

 

 

2 Array Formats of 6 Catalysts and 4 Bases

 

 

 

 

 

HCK1003-01-001

  • contains bases in aqueous solution
  • Array Format of 6 Catalysts and 4 Bases

 

 

HCK1003-01-004

  • contains solid anhydrous bases premixed with the catalysts
  • Array Format of 6 Catalysts and 4 Bases

 

 

 

Suzuki-Miyaura Cross-Coupling Screnning Kits

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